Comparative Efficacy of Triple Versus Quadruple Therapy for the Eradication of <i>Helicobacter pylori</i> Infection in Asian Adults-A Systematic Review and Meta-Analysis.

ABSTRACT: Helicobacter pylori infection remains a major health issue in Asia due to its strong association with gastric ulcers and cancer. Rising antibiotic resistance has reduced the success of standard triple therapy, leading to broader use of bismuth-based quadruple regimens. However, the relative effectiveness of these regimens in Asian populations remains uncertain. To evaluate which treatment is more effective in Asian populations, this systematic review and meta-analysis assessed randomized controlled trials comparing these two regimens. A comprehensive search across four major databases (PubMed, Web of Science, The Cochrane Library, and Scopus) up to May 2024 retrieved 16,398 studies. After thorough title and abstract (TIAB) and full-text screening, nine eligible studies involving 226

SUBMITTER: Razzak A 

PROVIDER: S-EPMC12483952 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature