JA-responsive R2R3-type MYB transcription factor OsMYB4P confers broad-spectrum antiviral immunity in rice.

ABSTRACT: Jasmonic acid (JA) plays a critical role in antiviral defence in rice, where viral infection activates JA signalling by degrading Jasmonate ZIM domain (JAZ) proteins, thereby releasing transcription factors (TFs) to drive JA-mediated defence gene expression. While the JA-responsive TF OsMYC2 has been extensively studied in rice, the involvement of MYB TFs in JA signalling remains largely unexplored. In this study, we identified a novel JA-responsive R2R3-type MYB TF OsMYB4P. OsMYB4P functions as a transcriptional activator, activating the expression of the JA synthesis gene CM-LOX1, and positively regulating rice sensitivity to JA. Additionally, OsMYB4P interacts with OsJAZs and is subject to transcriptional inhibition by OsJAZs. Overexpression of OsMYB4P (OE-OsMYB4P) enhances rice resista

SUBMITTER: Lu M 

PROVIDER: S-EPMC12483970 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature