Optic nerve sheath diameter for prediction of intracranial hypertension after ischemic sTrokE - The ONSITE study.

ABSTRACT:

Background

Intracranial hypertension (IH) from brain edema is a life-threatening complication of large vessel occlusion (LVO) stroke, yet clinical monitoring is often unreliable. Non-invasive methods for early IH prediction are needed. This study assessed whether sonographic measurement of the optic nerve sheath diameter (ONSD) could improve the prediction of IH after stroke.

Patients and methods

We prospectively measured the internal optic nerve sheath diameter (ONSDint) via transorbital ultrasound in 65 stroke patients and 30 controls. ONSD was also measured on the initial CT or MRI. The primary endpoint of IH was a composite of clinical and radiological signs of brain swelling. A predictive ONSD cut-off was determined from a multivariable logistic regression model, adjust

SUBMITTER: Baumgartner P 

PROVIDER: S-EPMC12484050 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature