Robotic-assisted total gastrectomy for refractory hypoproteinemia in Menetrier's disease: a case report with operative video and literature review.

ABSTRACT: Ménétrier's disease is a rare, progressive disorder of unclear etiology, typically affecting middle-aged men and characterized by giant gastric mucosal folds, mainly in the fundus and body, with occasional antral involvement. Diagnosis is challenging due to its rarity and the need to differentiate from hypertrophic lymphocytic gastritis, Zollinger-Ellison syndrome, gastric cancer, and lymphoma. We report a young male with Menetrier's disease presenting as generalized edema due to hypoproteinemia. After a challenging diagnostic process and ineffective medical management, the patient underwent robot-assisted total gastrectomy with Roux-en-Y esophagojejunostomy, which corrected the hypoproteinemia. He recovered uneventfully and was discharged on postoperative day 12. At 23 months post-surgery

SUBMITTER: Wang L 

PROVIDER: S-EPMC12484214 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature