Cholecystitis associated with Q fever: case report and systematic review.

ABSTRACT:

Background

Coxiella burnetii is an underestimated cause of acalculous cholecystitis. Large studies recently allowed to identify a dose-dependent association with IgG anticardiolipin. The management and long-term complications of Q fever-associated cholecystitis remain to be determined.

Methods

We describe a surgical case from Martigues, France, which is an endemic area and performed a systematic review of C. burnetii cholecystitis cases associated with Q Fever.

Results

Twenty-seven patients were included, including 3 (11.1%) children. All cases were reported during acute Q fever, followed by recurrent pancreatitis and chronic cholecystitis in 1 (3.7%) case. Two (2/2, 100%) were proven by a positive PCR on gallbladder but immunohistochemistry was negative in all cases.

SUBMITTER: Stheme de Jubecourt A 

PROVIDER: S-EPMC12484248 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature