Potential antioxidant and anti-inflammatory impacts of Salvia officinalis leaves extract on mice experimentally infected with Trichinella spiralis.

ABSTRACT: Trichinellosis is a dangerous food-borne zoonotic infection with a global spread. Treatment is currently insufficient. The study aimed to assess the potential therapeutic effects of Sage (Salvia officinalis) leaves extract in comparison to albendazole against Trichinella spiralis infection in mice. Seventy mice were classified into six groups, non-infected control, non-infected receiving Salvia officinalis extract, infected control, infected and treated with albendazole (50 mg/kg), infected and received Salvia officinalis extract (250 mg/kg), and infected and treated with combination of 25 mg/kg albendazole and 250 mg/kg S. officinalis extract. Mice were sacrificed at 7- and 37-days post-infection for intestinal and muscle phases, respectively. Efficacy was assessed through parasitological

SUBMITTER: Safi-Eldin M 

PROVIDER: S-EPMC12484373 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature