Endoscopy and noninvasive tests in pediatric disorders of gut-brain interaction: A multicenter retrospective study of the Italian Society of Pediatric Gastroenterology, Hepatology, and Nutrition.

ABSTRACT:

Objectives

Disorders of gut-brain interactions (DGBIs) are highly prevalent in pediatric gastroenterology and often lead to the use of invasive and noninvasive diagnostic tests, despite the guidance provided by the Rome IV criteria. Rome IV promotes a positive diagnostic approach based on the identification of specific symptoms occurring at defined frequencies, unexplained after thorough medical evaluation. This study aimed to evaluate the frequency and diagnostic accuracy of these tests in pediatric DGBIs.

Methods

We conducted a retrospective analysis of pediatric patients (aged 2-16 years) evaluated for suspected DGBIs, as defined by the Rome IV criteria, across five national pediatric gastroenterology centers. Patients with known underlying organic gastrointestinal diseas

SUBMITTER: Spatuzzo M 

PROVIDER: S-EPMC12484704 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature