Retrospective Study on CO₂ Laser for Second-Line Treatment of Vulvar Lichen Sclerosus.

ABSTRACT:

Background

Vulvar Lichen Sclerosus (VLS) represents a persistent inflammatory disease of the skin that particularly affects the genital area.

Aim

The study purpose was to investigate the effectiveness of CO₂ laser as a treatment of recalcitrant VLS. The parameters examined included treatment tolerance, patient satisfaction, symptoms, and VLS clinical markers.

Methods

This retrospective study enrolled 85 adult women affected by Vulvar Lichen Sclerosus (VLS), refractory to local corticosteroids. Patients were treated with three sessions of fractional CO₂ laser treatment at 4-week intervals. For vulvovaginal treatment, a device with a scanning handpiece and dedicated probes was used. The effectiveness of the treatment was evaluated at 1 month follow

SUBMITTER: Siliquini GP 

PROVIDER: S-EPMC12484719 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature