Epigenetic aging acceleration among World Trade Center-exposed community members.

ABSTRACT: Aging is a complex biological process, and some individuals are aging faster or slower than expected. This phenomenon of aging acceleration occurs when biological age exceeds chronological age and can be assessed by epigenetic clock estimation. As aging acceleration is known to occur in response to some environmental exposures as well as trauma, we hypothesized that World Trade Center (WTC) exposures may have led to epigenetic aging acceleration. WTC-exposed women were selected from the World Trade Center Environmental Health Center (WTC EHC) clinic, with peripheral blood collected during routine clinical monitoring visits. The reference group was selected from the NYU Women's Health Study (NYUWHS), a prospective cohort study that collected blood samples before 9/11/2001. Epigenomes of WTC

SUBMITTER: Tuminello S 

PROVIDER: S-EPMC12484928 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature