Characterization of vaginal prokaryotes and eukaryotes microbiota and its link to sexually transmitted infections.

ABSTRACT: The vaginal microbiota plays a critical role in maintaining reproductive health. Although Lactobacillus species often dominate the vaginal environment in healthy individuals, recent studies have shown that healthy microbiota compositions can also include Lactobacillus-depleted states, as described by the Community State Types (CSTs) framework. However, disruptions in the microbiota composition, such as those caused by sexually transmitted infections (STIs), can lead to increased diversity and instability, compromising host protection. This study investigates the association between vaginal microbiota composition and the prevalence of STIs in a cohort of incarcerated women in Chile. Using metataxonomic approaches targeting 16S and 18S rRNA genes, we characterized prokaryotic and eukaryotic

SUBMITTER: Moya-Beltran A 

PROVIDER: S-EPMC12485140 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature