Nomogram for predicting early olfactory dysfunction in obstructive sleep apnea-hypopnea syndrome: a multicenter-based study.

ABSTRACT:

Objective

To develop and validate a clinical prediction model for olfactory dysfunction in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS), evaluating the combined predictive value of polysomnography (PSG) parameters and clinical symptoms.

Methods

We retrospectively analyzed 546 OSAHS patients, including 420 from the Affiliated Hospital of North Sichuan Medical College were [randomly divided into training (n = 294) and internal validation (n = 126) sets], and 126 from the Sixth People's Hospital of Chengdu (external validation set). All patients underwent overnight PSG for sleep parameter assessment and Sniffin' Sticks tests for olfactory evaluation. Predictors were selected using LASSO regression with subsequent logistic regression modeling, fo

SUBMITTER: Pan Q 

PROVIDER: S-EPMC12485232 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature