Pheochromocytoma and heart rate variability: a systematic review and meta-analysis.

ABSTRACT:

Introduction

Pheochromocytoma is a catecholamine-producing tumor, that may alter cardiovascular activity. Conveniently, sympathovagal activity can be measured non-intrusively and pain-free through heart rate variability (HRV).

Objective

To conduct a systematic review and meta-analysis on the impact of pheochromocytoma on HRV parameters.

Methods

PubMed, Cochrane, Embase and Google Scholar were searched until October 10, 2024 for articles reporting HRV parameters in pheochromocytoma patients. Random-effects meta-analysis were conducted on each HRV parameters stratified on pheochromocytoma patients and controls and then comparing these two groups: RR intervals (or Normal-to-Normal intervals-NN), SDNN (Standard Deviation of RR intervals), RMSSD (square root of the mean di

SUBMITTER: Dutheil F 

PROVIDER: S-EPMC12485537 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature