Altered static and dynamic functional connectivity in childhood basic-type intermittent exotropia.

ABSTRACT: This study aimed to investigate static and dynamic functional connectivity alterations between the primary visual cortex, secondary visual cortex, higher visual cortex and oculomotor cortex in children with basic-type intermittent exotropia. A total of 44 children with basic-type intermittent exotropia and 37 healthy controls matched for sex, age and education level were included and underwent resting-state functional MRI. Both sides of Brodmann area (BA) 17, BA18, BA19 and BA8 were chosen as regions of interest. Sliding window method and k-means clustering analysis were employed to investigate static and dynamic functional connectivity as well as temporal metrics based on visual cortices and oculomotor cortices. Differences in functional connectivity and temporal metrics were ident

SUBMITTER: Zhou M 

PROVIDER: S-EPMC12485606 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature