Cohort profile: A community-based prospective cohort study of Alzheimer's disease and related dementias in the Democratic Republic of Congo.

ABSTRACT:

Introduction

The Étude du Vieillissement Cognitif et de Démence en République Démocratique du Congo (Study of Cognitive Aging and Dementia in the Democratic Republic of Congo, EVCD-RDC) was launched in 2024 to characterize cultural, biological, and environmental risk factors of cognitive aging and dementia in Kinshasa.

Methods

The study is enrolling 800 adults aged ≥65 years across four diagnostic groups (cognitively unimpaired, mild cognitive impairment, Alzheimer's disease [AD], and other dementias). Recruitment occurs through community and clinical settings. Assessments include neuropsychological testing, neurological examination, social determinants, biospecimen collection, and air pollution exposure, with follow-up every two years.

Results

To date, 506 par

SUBMITTER: Ikanga J 

PROVIDER: S-EPMC12485996 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature