The Modern Utility of Awake Deep Brain Stimulation Surgery.

ABSTRACT:

Background

Awake deep brain stimulation (DBS) surgery with microelectrode recording (MER) and test stimulation offers real-time physiologic feedback to refine lead placement, but its relevance is increasingly debated in an era of advanced imaging and streamlined asleep workflows.

Objective

To describe a contemporary framework for awake DBS with MER and to evaluate whether, in our hands, this approach results in a final lead position different from what we would have achieved with asleep DBS.

Methods

We outline a standardized workflow combining high-resolution imaging, confirmatory MER, and intraoperative stimulation mapping for an example context of thalamic targeting for essential tremor. To quantify the impact of the awake approach on surgical decision making, we re

SUBMITTER: Klassen BT 

PROVIDER: S-EPMC12486036 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature