Difference in outcome event coverage between insurance-based and hospital-based databases: a methodological study of diabetes drug use and cardiovascular events in Japan.

ABSTRACT:

Introduction

In countries with unrestricted access to healthcare, such as Japan, patients may initiate a drug at a clinic or hospital and then may visit another hospital when outcome events occur. Theoretically, an insurance-based database can capture all outcomes, whereas a hospital-based database can only capture outcomes when patients visit that hospital. We examined the difference in outcome event coverage between insurance-based and hospital-based databases in Japan, and its impact on pharmacoepidemiology studies, using diabetes drug use and cardiovascular events as an example.

Methods

Using the JMDC payer database, we identified new users of sodium-glucose cotransporter-2 (SGLT2) inhibitors or dipeptidyl peptidase-4 (DPP-4) inhibitors as the first choice of treatment f

SUBMITTER: Ando T 

PROVIDER: S-EPMC12486410 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature