Zoster-associated pain: pretreatment time interval is inversely associated with pulsed radiofrequency effectiveness in a retrospective mono-institutional analysis.

ABSTRACT:

Background

Pulsed radiofrequency (PRF) is an effective treatment for herpes zoster-associated pain (ZAP), the optimal time to perform the PRF treatment remains unclear. This study aimed to explore this relationship and determine the optimal timing for PRF intervention.

Methods

This research conduct a single-center retrospective cohort study in China. 303 patients who received PRF treatment for ZAP were followed up for 3 months. The primary endpoints were numerical rating scale (NRS) score and NRS reduction rate. Multiple assessment scales were used to evaluate pain and symptoms. Cox regression analysis and restricted cubic spline analysis were performed to examine the relationship between pre-treatment time interval (PTI) and outcomes.

Results

69.9% achieved positive

SUBMITTER: Guo X 

PROVIDER: S-EPMC12486548 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature