Body composition, bone mineral density, and functional impairment in axial spondyloarthritis: a 36-month longitudinal study.

ABSTRACT:

Background

Axial spondyloarthritis (ax-SpA) is a chronic inflammatory disease affecting the axial skeleton, peripheral joints, And entheses, often leading to pain, stiffness, And extra-articular complications. Its impact on muscle and bone health has gained attention, as chronic inflammation, reduced physical activity, sedentary behaviour, and glucocorticoid therapy, may alter body composition, particularly lean mass and adipose tissue distribution. This study explores the association between disease activity, body composition, and bone parameters in ax-SpA patients over a 36-month period.

Methods

This longitudinal study was conducted at Padua University Hospital (Italy). The following data was collected at baseline And 36 months: medical history, phospho-calcium metabolism,

SUBMITTER: Ceolin C 

PROVIDER: S-EPMC12486735 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature