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Spontaneous pneumomediastinum and/or pneumothorax in anti-MDA5 dermatomyositis: a refined staging system.


ABSTRACT:

SUBMITTER: Jin J 

PROVIDER: S-EPMC12486751 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature

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Spontaneous pneumomediastinum and/or pneumothorax in anti-MDA5 dermatomyositis: a refined staging system.

Jin Jiajia J   Xu Wenwen W   Wang Huijing H   Wang Xiaodong X   Fu Qiong Q   Wu Wanlong W   Ye Shuang S  

Respiratory research 20251001 1


BACKGROUND: Spontaneous pneumomediastinum and/or pneumothorax (SPM/P) have been Linked to unfavorable outcome in anti-melanoma differentiation-associated gene 5 positive dermatomyositis (MDA5+DM) patients. This study attempted to investigate the prognostic value of SPM/P and identify the predisposing factors of SPM/P in patients with interstitial lung disease (ILD) complicated with MDA5+DM. METHODS: This study was conducted in a large inception cohort of MDA5+DM-ILD (from 2014 to 2023) at Shangh  ...[more]

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