Risk of intrauterine transmission and pregnancy outcomes following SARS-CoV-2 infection in the first or second trimester: a prospective cohort study.

ABSTRACT:

Background

China encountered a nation-wide outbreak of SARS-CoV-2 transmission during December 2022-January 2023 after discontinuation of the strict zero-Covid-19 policy on December 7, 2022. However, data on its impact on early pregnancy was limited. We aimed to investigate the risk of intrauterine transmission and pregnancy outcomes following SARS-CoV-2 infection during the first or second trimester, and to assess the safety of post-infection amniocentesis.

Methods

From January 31 to February 28, 2023, we prospectively invited all pregnant women who were referred for amniocentesis to perform chromosomal microarray analysis to participate in this study. Based on the infection time, the participants were divided into group one with Covid-19 in the first trimester and and grou

SUBMITTER: Zhu X 

PROVIDER: S-EPMC12487027 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature