Characterization of normative fetal rhesus macaque brain development with magnetic resonance imaging.

ABSTRACT: Advances in motion correction magnetic resonance imaging methods have made it possible to track anatomical changes throughout the highly dynamic phase of fetal neurodevelopment. Characterizing the trajectory of normative brain development provides insight into the underlying biological processes driving growth, as well as a framework for identifying deviations that may be etiological markers of neurodevelopmental disorders. Rhesus macaques, which exhibit similar gestational neurodevelopmental timelines to humans, can be used to address the challenges of obtaining accurate longitudinal fetal imaging measurements and are a key preclinical resource for investigating experimental developmental perturbations. Additionally, the ability to examine biological factors including age and sex can prov

SUBMITTER: Karpf JA 

PROVIDER: S-EPMC12487360 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature