Association between history of pregnancy loss and preterm birth: the mediating role of maternal anxiety.

ABSTRACT:

Background

A history of pregnancy loss may elevate maternal anxiety in subsequent pregnancies. Both prior pregnancy loss and maternal anxiety are associated with an increased risk of preterm birth. However, the role of maternal anxiety in the association between a history of pregnancy loss and preterm birth remains unclear. In this study, we aim to investigate the association among history of pregnancy loss, maternal anxiety, and preterm birth and to explore the potential mediating effect of maternal anxiety on this relationship.

Methods

This retrospective cohort study included 109 preterm and 558 term births between January 2021 and October 2023. We collected data on maternal history of pregnancy loss and pregnancy outcomes from electronic medical records. Maternal anxiety

SUBMITTER: Wang Y 

PROVIDER: S-EPMC12487446 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature