Dataset Information
Development of a prognostic model based on seven mitochondrial autophagy- and ferroptosis-related genes in lung adenocarcinoma.
Ontology highlight
ABSTRACT:
SUBMITTER: Zhao YN
PROVIDER: S-EPMC12487532 | biostudies-literature | 2025 Oct
REPOSITORIES: biostudies-literature
Publications
Development of a prognostic model based on seven mitochondrial autophagy- and ferroptosis-related genes in lung adenocarcinoma.
BMC medical genomics 20251001 1
BACKGROUND: Lung adenocarcinoma (LUAD) is a leading cause of cancer-related mortality globally, necessitating finding novel therapeutic targets. Mitochondrial autophagy (mitophagy) and ferroptosis have emerged as promising avenues in cancer research. This study aimed to identify mitophagy- and ferroptosis-related genes (MiFeRGs) in LUAD and develop a prognostic risk model based on these genes. METHODS: Integration of transcriptomic data from the TCGA dataset with MiFeRG databases was performed. ...[more]