Magnitude and predictors of gestational trophoblastic disease in East Africa: a systematic review and meta-analysis.

ABSTRACT:

Introduction

Gestational Trophoblastic Disease (GTD) encompasses a spectrum of placenta-related disorders with significant health risks. Despite the varying reported prevalence rates in East Africa, no comprehensive meta-analysis has been conducted to synthesize the overall burden and predictors of GTD in this region.

Methods

Following the PRISMA guidelines, we conducted a systematic review and meta-analysis of studies from PubMed, Cochrane Library, and Google Scholar (search period: 2000-2024). We assessed heterogeneity (I² and Q tests), pooled estimates using a random-effects model, and evaluated publication bias using funnel plots and Egger's test. A sensitivity analysis was performed to test the robustness of the findings.

Results

Eleven studies were in

SUBMITTER: Yilak G 

PROVIDER: S-EPMC12487570 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature