The initial report of prospective study for maternal and fetal outcomes to investigate the safety of multifetal pregnancy reduction in Japan.

ABSTRACT:

Aim

This study aimed to establish the safety of multifetal pregnancy reduction (MFPR) and examine its complications, patient background, and psychological impact.

Methods

This single-center, single-arm, prospective intervention study included 10 women who were treated at our institution between April and December 2024. The indications were triplet or higher-order multiple pregnancies, as well as twin pregnancies with serious maternal complications. Procedures were performed between 11 and 13 gestational weeks, and the patients were observed for up to 1 week postoperatively. The primary outcome was the completion ratio at hospital discharge, whereas the secondary outcomes were the survival rate of non-targeted fetuses, the number of adverse events, and the psychological evalu

SUBMITTER: Wakui N 

PROVIDER: S-EPMC12487742 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature