Bilateral Lower Limb Acute Compartment Syndrome Related to Drug Abuse: Two Case Reports.

ABSTRACT: Acute compartment syndrome (ACS) is typically observed in a unilateral limb, whereas bilateral lower limb ACS is rare, and few cases are reported. We report 2 cases of bilateral lower limb ACS induced by drug abuse and prolonged Japanese traditional Seiza position. Case 1 involved a 34-year-old man who developed bilateral lower limb ACS after prolonged Seiza sitting while under the influence of amphetamines. He underwent bilateral fasciotomy but required below-knee amputation due to infection. Case 2 involved a 31-year-old man found unconscious in the Seiza position for 11 hours after a suspected benzodiazepine overdose. Despite fasciotomy, he required staged amputations due to poor wound healing. We believe that prolonged Seiza, a traditional Japanese sitting posture, is a key factor in b

SUBMITTER: Matsuda T 

PROVIDER: S-EPMC12487932 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature