Midlife and old-age cardiovascular risk factors, educational attainment, and cognition at 90-years - population-based study with 48-years of follow-up.

ABSTRACT: We examined the associations of midlife and old-age cardiovascular risk factors, education, and midlife dementia risk scores with cognition at 90 + years, using data from a population-based study with 48 years of follow-up. Participants were 96 individuals aged 90-97 from the older Finnish Twin Cohort study. Individual cardiovascular risk factors assessed via questionnaires in 1975, 1981, 1990, and 2021-2023 included blood pressure, body mass index, physical activity, and cholesterol, and self-reported educational attainment. The Cardiovascular Risk Factors, Aging, and Dementia (CAIDE) score and an educational-occupational attainment score were used as midlife dementia risk scores. Cognitive assessments included semantic fluency, immediate and delayed recall from a 10-word list learning ta

SUBMITTER: Varjonen A 

PROVIDER: S-EPMC12488009 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature