New <i>Streptomyces</i>-Derived Antibacterial Compounds Targeting Gram-Positive Bacteria: A Systematic Review.

ABSTRACT: Bacterial infections, particularly those caused by Gram-positive bacteria like vancomycin-resistant enterococci (VRE) and methicillin-resistant Staphylococcus aureus (MRSA), are a growing concern. This review highlights the potential of the Streptomyces genus in producing novel antibacterial compounds against Gram-positive bacteria. The study was carried out following the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA). To gather relevant literature on novel anti-Gram-positive bacteria compounds produced by Streptomyces, a web search was conducted using several databases, including Scopus, PubMed, ScienceDirect, and Google Scholar, covering the period from January 2013 to mid-2024. The search terms employed in this study in

SUBMITTER: Ait Assou S 

PROVIDER: S-EPMC12488318 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature