Association between triglyceride-glucose index and sarcopenia in patients with chronic kidney disease.

ABSTRACT:

Objective

This study aimed to examine the relationship between the triglyceride-glucose index (TyG) and sarcopenia in patients with chronic kidney disease (CKD). The aim was to gain new insights into preventing and treating sarcopenia in CKD patients.

Methods

The study utilized data from two cohorts, including the NHANES 2011-2018 cohort in the United States and the 2018-2023 cohort in China. After applying uniform inclusion and exclusion criteria, 827 patients with CKD in the US cohort and 1,038 patients with CKD in the Chinese cohort were ultimately included in the study. The relationship between the TyG index and sarcopenia was analyzed using logistic regression modeling and multivariate adjustment. The dose-response relationship was also explored using restricted cubic s

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC12488414 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature