Triglyceride glucose index - body mass index predicts insulin resistance, metabolic syndrome and associates with impaired ovulation in Chinese women with polycystic ovary syndrome.

ABSTRACT:

Background

Insulin resistance (IR) and metabolic syndrome (MetS) are highly prevalent and pathophysiologically central features of polycystic ovary syndrome (PCOS). However, their assessment is challenged by the limitations of gold-standard diagnostic methods. The clinical utility of the novel triglyceride glucose index - body mass index (TyG-BMI) for predicting IR, MetS, and its association with fertility outcomes in Chinese women with PCOS remains unexplored and warrants investigation.

Objective

To evaluate the association between TyG-BMI and IR and MetS, and fertility outcomes in women with PCOS.

Methods

We used data of 855 participants of the Acupuncture and Clomiphene for Chinese Women with Polycystic Ovary Syndrome (PCOSAct) trial. Linear trend tests and logisti

SUBMITTER: Guan M 

PROVIDER: S-EPMC12488453 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature