Large artery atherosclerotic versus cardioembolism subtypes of large hemispheric infarction in the middle cerebral artery.

ABSTRACT:

Background

Large hemispheric infarction (LHI) of the middle cerebral artery (MCA) is linked to high mortality and morbidity. This study aims to investigate the characteristics of large artery atherosclerosis (LAA) and cardioembolism subtypes of LHI in MCA.

Methods

This retrospective cohort study included 70 patients with LHI hospitalized at the Second Affiliated Hospital of Anhui Medical University from May 2019 to May 2021. Patients were classified according to the TOAST classification into LAA and cardioembolism subtypes.

Results

Among the 70 patients, 44 were identified with the LAA subtype (aged 76.00 years, 50% were male) and 26 with cardioembolism (aged 71.50 years, 57.1% were male). The LAA group exhibited significantly higher rates of hyperhomocysteinemia (18.

SUBMITTER: Xiao H 

PROVIDER: S-EPMC12488826 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature