Purine-based chemical probe with HOMO switching for intracellular detection of mercury ions.

ABSTRACT: The detailed photophysical characterization of 2-piperidinyl-6-triazolylpurine derivatives and their complexes with metal ions is presented. The studied compounds contain two electron donating units - piperidine and methoxyphenyl, while triazolyl-purine acts as an electron acceptor. These derivatives possess good fluorescence quantum yields in both aprotic and aqueous environments. All piperidine-triazole-purine compounds exhibited a fluorescence "turn-off" sensing behavior to different metal ions, including Hg²⁺. We are discussing the changes in photophysical properties occurring upon complexation including switching between highest occupied molecular orbitals (HOMOs) of different electron donating units and the entire electron charge shift possibility in the complex with mercu

SUBMITTER: Boguseviciene K 

PROVIDER: S-EPMC12488857 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature