Cytokine concentrations in people with eating disorders: A comprehensive updated systematic review and meta-analysis.

ABSTRACT:

Background

Prior research has found altered levels of cytokines in people with eating disorders (EDs). This study is an update of a previous meta-analysis, including longitudinal analyses and machine learning heterogeneity analyses (MetaForest).

Methods

This pre-registered ( https://osf.io/g6d3f ) systematic review and meta-analysis following PRISMA guidelines assessed studies from four databases (PubMed, Web of Science, MEDLINE, PsycINFO) reporting cytokine concentrations in people with EDs until 10^th November 2024. Random-effects models were utilised for all meta-analyses.

Results

Twenty-four new studies are incorporated, resulting in a total of 43 studies included in meta-analyses. Interleukin (IL)-6 and IL-15 are higher, and IL-7 lower, in anorexia nerv

SUBMITTER: Keeler JL 

PROVIDER: S-EPMC12488998 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature