Long-term exposure to ambient PM₁ accelerates biological aging in middle-aged and older adults in China.

ABSTRACT: Population aging poses significant public health challenges in China. Emerging studies have linked air pollution to physiological aging, yet evidence regarding particulate matter with an aerodynamic diameter ≤ 1 μm (PM₁) remains sparse. This two-wave panel study included 5391 Chinese adults aged 45-80 to explore the effects of long-term exposure to PM₁ on biological aging acceleration. The Klemera-Doubal method (KDM) was employed to estimate biological aging acceleration (KDM-BAA) using 11 clinical biomarkers at both the 2011 baseline and the 2015 follow-up survey. Multivariate linear models with natural cubic splines were performed to estimate the association between PM₁ exposure and KDM-BAA changes from baseline to follow-up. Sensitivity analyses and stra

SUBMITTER: Ke J 

PROVIDER: S-EPMC12489009 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature