Clinicopathological characteristics and treatment of patients with colorectal neuroendocrine carcinoma: A retrospective study of 157 cases.

ABSTRACT: The present study sought to explore the clinicopathological characteristics, and construct a prognostic nomogram predicting disease-free survival (DFS) and overall survival (OS) in patients with colorectal neuroendocrine carcinoma (CRNEC). Data of patients diagnosed with CRNEC from Harbin Medical University Cancer Hospital (Harbin, China) between January 2000 and December 2019 were retrospectively collected. These patients were randomly divided into different groups by histological type, differentiation grade and AE1/AE3 expression. Subsequently, χ² test and Fisher's exact test were employed to assess associations between categorical variables and multiple groups, Kaplan-Meier estimates were generated to analyze survival, and univariate and multivariate Cox proportional hazards

SUBMITTER: Dai M 

PROVIDER: S-EPMC12489527 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature