Dosimetric impact of dose constraint indications using individual patient dose management system for brachytherapy in cervical cancer.

ABSTRACT:

Purpose

Total dose assessment for cervical cancer necessitates converting external beam radiotherapy (EBRT) and brachytherapy (BT) doses to equivalent doses in 2 Gy fractions (EQD₂), and compare them with dose constraints. However, this feature is absent in current treatment planning systems. To address this, we developed a system fulfilling this need, and evaluated its dosimetric impact.

Material and methods

The system can assess total dose by considering EQD₂ for targets and organs at risk (OARs), and provide ideal fractionated dose that satisfies dose constraints in each process. The current retrospective study included 82 cervical cancer patients treated with EBRT and four BT fractions. Forty-one patients were assigned to either of two groups (with

SUBMITTER: Chiba T 

PROVIDER: S-EPMC12489536 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature