Motor and default mode network states of rest in frontal lobe epilepsy.

ABSTRACT: Frontal lobe epilepsy (FLE), marked by recurrent seizures arising from the frontal lobes, can significantly impair cognitive and motor function, reducing quality of life. Recent studies suggest that epilepsies can involve functional networks throughout the brain that can be identified using resting-state functional magnetic resonance imaging (fMRI). In this study, we aimed to determine whether FLE is associated with a distinct functional network brain states. Using dynamic functional connectivity analysis in combination with k-means clustering, we investigated dynamic connectivity patterns of the somatomotor network (SMN) and default mode network (DMN) of ten right-hemisphere and six left-hemisphere FLE patients, as well as nine healthy controls. We found two distinct states of rest

SUBMITTER: Rashnavadi T 

PROVIDER: S-EPMC12489773 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature