Fabrication of Flexible 3D Electrospun Poly(trimethylene carbonate) Scaffolds with Superior Cellular Infiltration for Tissue Engineering.

ABSTRACT: Although electrospinning has garnered significant attention, most studies focus on thermoplastic materials. The adaptation of elastomeric materials for electrospinning presents challenges, particularly due to their viscous behavior at room temperature (RT). In the present study, we introduce a versatile method for electrospinning rubber-like polymer poly-(trimethylene carbonate) (PTMC) utilizing an ethanol collector bath. Traditional electrospinning primarily yields sheet-like fibrous meshes, failing to create a three-dimensional scaffold with structural integrity. Here, we present an innovative approach to transform 2D fibrous meshes into 3D fibrous scaffolds. Both scanning electron microscopy and X-ray analysis confirmed that the resulting 3D scaffolds possess a fibrous structure with a

SUBMITTER: Zhang M 

PROVIDER: S-EPMC12489843 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature