Increased GII.3[P12] norovirus outbreaks and viral whole genome analysis in Beijing, China during 2021 and 2023.

ABSTRACT:

Background

Norovirus is the predominant pathogen responsible for global acute gastroenteritis outbreaks and sporadic cases. While GII.3[P12] norovirus is typically associated with sporadic cases of acute gastroenteritis, outbreaks caused by this genotype increased sharply in Beijing from 2021 to 2023. This study aimed to characterize the GII.3[P12] norovirus outbreaks in Beijing from August 2021 to July 2023, analyze whole-genome sequences, and infer spread dynamics.

Results

GII.3[P12] outbreaks primarily occurred in winter and spring (90.68%, 107/118), concentrated in urban areas (56.78%, 67/118). Ninety-three outbreaks (78.81%, 93/118) were reported in kindergartens. Person-to-person transmission was the main route, accounting for 99.14% (115/116) of outbreaks with a defin

SUBMITTER: Fu J 

PROVIDER: S-EPMC12490128 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature