Effectiveness and safety of brivaracetam in comparison with levetiracetam in seizures.

ABSTRACT:

Background

There are increasing incidence of psychiatric side effects associated with the use of anti-epileptics. Prospective observational studies on the effectiveness and safety of levetiracetam (LEV) and brivaracetam (BRV), along with the haematological abnormalities of both treatments, in seizure patients in an Indian population are lacking. Therefore, we aimed to compare the effectiveness and safety of LEV and BRV in seizure patients and evaluated behavioural and non-behavioural side effects, as well as outcomes when switching between LEV and BRV.

Methods

A prospective observational study was conducted in newly diagnosed as well as previously diagnosed patients (n = 115) with epilepsy aged ≥ 5 years of age receiving LEV (n = 66) or BRV (n = 49). Baseline data were colle

SUBMITTER: Sivadasan S 

PROVIDER: S-EPMC12490144 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature