In-Petri-Dish Traveling and Standing Acoustic Wave-Assisted Fabrication of Anisotropic Collagen Hydrogels.

ABSTRACT: Anisotropic biomaterials containing oriented collagen fibers have shown great potential for various biomedical research areas, such as wound dressing, corneal grafting, and the study of cancer cell invasion in biomimetic microenvironments. To fabricate such anisotropic biomaterials, previous studies have used electric, microfluidic, magnetic, and mechanical methods to align collagen fibers during the fabrication process. In this study, we put forward traveling and standing acoustic wave-based approaches that enable the rapid in-Petri-dish fabrication of anisotropic biomaterials containing acoustically arranged collagen fibers. To develop these approaches, we investigated the effects of traveling and standing acoustic waves on collagen self-assembly and the micro/nanoscale architectures of

SUBMITTER: Du Y 

PROVIDER: S-EPMC12490268 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature