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Interstitial lung disease epidemiology and etiology in patients with solid malignant tumors: a systematic literature review.


ABSTRACT:

Background

Interstitial lung disease (ILD) can occur in patients with cancer. ILD can be caused by anti-cancer treatments (drug-induced [DI] ILD), but also by opportunistic infection, and non-drug-related etiologies. This systematic literature review (SLR) investigated the epidemiology and etiology of non-DI ILD and DI ILD management and outcomes in patients with solid cancers.

Methods

Databases were searched to August 2023 using terms for ILD and solid cancers. Relevant congresses held 2021-2023 and SLR bibliographies were hand-searched. Records were screened by two independent reviewers. Inclusion criteria comprised ILD epidemiology outcomes, ILD clinical management, and survival outcomes.

Results

Of 4,519 unique records screened, 55 full texts were included (six fr

SUBMITTER: Smit EF 

PROVIDER: S-EPMC12490398 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature