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Sex differences in guideline-based statin utilization and recurrent events in patients with known coronary artery disease.


ABSTRACT:

Introduction

Current guidelines recommend using high-intensity statins in patients with atherosclerotic cardiovascular disease (ASCVD). Guideline directed statin intensity (GDSI) implementation and ASCVD outcomes may differ by sex. We evaluated sex-based differences in GDSI use and recurrent ASCVD outcomes in a large healthcare network.

Methods

Using electronic medical records, we assessed statin use and intensity in a cohort of patients with established coronary artery disease (coronary artery bypass grafting or percutaneous coronary intervention) between 2010-2022. Statins were categorized into GDSI (high intensity),

SUBMITTER: Koczo A 

PROVIDER: S-EPMC12490523 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature