Nerve Repair for Erectile Dysfunction After Radical Prostatectomy: A Systematic Review of Outcomes.

ABSTRACT:

Background

Erectile dysfunction (ED) is a prevalent complication after radical prostatectomy (RP), affecting up to 89% of patients within 2-5 years due to cavernous nerve injury. Nerve grafting has been proposed as a strategy to restore erectile function, but outcomes remain inconsistent, and randomized controlled trials have yielded mixed results. This review evaluated the effectiveness of nerve grafting techniques for ED management after RP.

Methods

A systematic search of PubMed, MEDLINE, and Embase databases was conducted using terms related to ED, nerve grafting, and cavernous nerve repair. From 239 initial studies, 17 met the inclusion criteria, focusing on human subjects and reporting outcomes of unilateral or bilateral nerve grafting with autologous donor nerves, such

SUBMITTER: Chrabieh E 

PROVIDER: S-EPMC12490649 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature