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Sexual Orientation Disparities in Subjective Cognitive Decline in a Large Cohort of Female Nurses.


ABSTRACT: Purpose: Sexual minority (SM) women have more dementia risk factors than heterosexual women, but it remains unknown whether they experience increased symptoms of subjective cognitive decline (SCD)-a key predictor of dementia. Methods: We investigated sexual orientation-related disparities in SCD in Nurses' Health Study II (N = 70,772). Sexual orientation subgroups included completely heterosexual (n = 62,884); participants identifying as heterosexual with same-sex experience ("heterosexual-SM", n = 5017); and participants identifying as mostly heterosexual (n = 1825), bisexual (n = 287), or lesbian/gay (n = 759). SCD was measured using seven symptoms from the Structured Telephone Interview for Dementia Assessment, contro

SUBMITTER: McKetta S 

PROVIDER: S-EPMC12490735 | biostudies-literature | 2025 Aug-Sep

REPOSITORIES: biostudies-literature