Causal association of dietary intake habits and telomere lengths: A Mendelian randomization study.

ABSTRACT:

Background and objectives

Healthy diets are crucial in disease prevention and balanced diets can slow te-lomere shortening. Currently, it is still unclear which dietary factors are causally related to telomere length.

Methods and study design

The inverse variance weighted, Mendelian Randomization-Egger, weighted median, simple mode, and weighted mode methods were used. Additionally, heterogeneity, pleiotropy, MR-PRESSO and leave-one-out tests were conducted to ensure accuracy. Outcomes included granulocyte, lym-phocyte, naive T-cell, memory T-cell, B-cell, and natural killer-cell telomere lengths. Exposures included alcohol intake frequency, alcoholic drinks per week, average weekly beer plus cider intake, average weekly red wine intake, intake of beef, bread, cereal, coffee

SUBMITTER: Chen J 

PROVIDER: S-EPMC12490951 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature