Immunohistochemical insights into hypothermia-related deaths: a systematic review.

ABSTRACT:

Purpose

Hypothermia occurs when core body temperature drops below 35 °C. The purpose of this review was to identify and analyze studies on the topic of hypothermia from an immunohistochemical perspective to determine robust markers of fatal hypothermia.

Methods

This systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) reporting guidelines. It has been registered with Prospero (registration number: CRD42024572782).

Results

In total, 2618 publications met the search criteria. A total of 63 duplicate articles were excluded and a further 2489 publications were excluded for not meeting the inclusion criteria, leaving 29 full-text articles. Furthermore, from the bibliographies of the included articles, four more publicat

SUBMITTER: Tomassini L 

PROVIDER: S-EPMC12491099 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature