New insights into carbon metabolism in S<i>pathaspora passalidarum</i> for second-generation ethanol production.

ABSTRACT: Bioethanol is a sustainable, low-impact energy source with the potential to reduce or even replace fossil fuel consumption. Second-generation (2G) bioethanol exploits lignocellulosic agro-industrial residues, contributing to circular economy strategies by valorizing these waste streams. However, conventional Saccharomyces cerevisiae strains are unable to efficiently metabolize the pentose sugars abundant in lignocellulose, prompting growing interest in non-conventional yeasts such as Spathaspora passalidarum. This species, recognized for its innate ability to assimilate pentoses, remains underexplored, particularly regarding its metabolic performance in mixed-sugar environments containing hexoses, pentoses, and disaccharides. Our results demonstrate that S. passalidarum

SUBMITTER: Racca S 

PROVIDER: S-EPMC12491191 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature