The effect of guideline-directed medicine on patients with new-onset heart failure following acute myocardial infarction.

ABSTRACT:

Aims

To investigate the impact of guideline-directed medical therapy (GDMT) during hospitalization on the prognosis of patients with heart failure (HF) episode complicating post-acute myocardial infarction (AMI).

Methods

From 01/05/2017 to 30/09/2022, 527 patients with HF episode complicating post-AMI at a single medical center who were retrospectively analyzed. Based on whether GDMT during hospitalization was used in patients undergoing percutaneous coronary intervention (PCI), the patients were divided into the GDMT group (n = 379) and the non-GDMT group (n = 148), with a follow-up period of 12 months after PCI. The primary endpoint was the composite endpoint of all-cause death and all-cause readmission.

Results

The incidence of the primary endpoints (

SUBMITTER: Lei M 

PROVIDER: S-EPMC12491194 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature