Metabolite profiling and free radical scavenging activity studies of alkaloids from Erythrina crista-galli twigs through in vitro and in silico analysis.

ABSTRACT: Erythrina crista-galli is among 130 species of genus Erythrina which widely distributed in Indonesia, Australia, Argentina, Uruguay, Paraguay, and Brazil. Among the botanical parts used for the exploration of alkaloids from E. crista-galli (cockspur coral, ceibo, corticeira), the twig being one that rarely explored. This study aims to explore the alkaloid content from the twig of E. crista-galli as well as to evaluate their free radical scavenging activities through in vitro and in silico studies. The metabolite profile of the ethanol extract from Erythrina crista-galli twigs was characterized using Ultra-Performance Liquid Chromatography coupled with Tandem Mass Spectrometry (UPLC-MS/MS). The structures of the isolated alkaloids were determined through Nuclear Magnetic Resonance (NMR) and

SUBMITTER: Akili AWR 

PROVIDER: S-EPMC12491411 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature